Novak Djokovic lost in the 2nd-round of the Australian Open to Uzbekistan's Dennis Istomin 7-6, 5-7, 2-6, 7-6, 6-4.
The last time the six-time Australian Open champion, Djokovic lost in the 2nd-round of a grand slam was at the 2008 Wimbledon and only the second time in seven years that he has lost to a player ranked outside the top 100 - his defeat by Juan Martin del Potro, ranked 145th, at the Rio Olympics in 2016 being the other occasion.
The world number 117, Istomin matched his best performance in the opening Grand Slam of the year with this shocking victory by advancing to the 3rd round.
"He deserved to win. No doubt, he was a better player in the clutch moments," Djokovic said.
"Many things came together for him today and he's a well-deserved winner. There's not much I could do."
Prior to his win over Djokovic, Istomin had won just one of 33 matches against a player ranked in the world's top 10.
'I surprised myself! It is the biggest win [of my career] for me and means so much, now I feel I can play with these guys and be with them on the same level," said Istomin.
Istomin will next face Spain's Pablo Carreno Busta, who beat Britain's Kyle Edmund on Thursday.
